Biomedical Media + Illustration

iNKT Cell Activation


Title: Direct and Indirect Activation of iNKT Cells
Media: Adobe Illustrator CS5
Audience: Undergraduate students and the research community
Format: 3/4 Page of an 8.5 x 11″ textbook illustration

The purpose of the illustration was to create a two-dimensional image to communicate a specific aspect of the research of Dr. Thierry Mallevaey from the Department of Immunology at the Univer- sity of Toronto. The image dynamically shows the two main pathways of invariant natural killer t-cell activation in a way that would be appropriate for use in lectures to students, publications, and presentations to colleagues. The illustration was presented to Dr. Mallevaey in both print (shown here) and projection formats for his own use.

Process Images:

References and Further Reading:

Matsuda JL, Mallevaey T, Scott-Browne J, Gapin L. CD1d-restricted iNKT cells, the ‘Swiss-Army knife’ of the immune system. Current Opinion in Immunology, 20: 358-368 (2008).

Paget C, Mallevaey T, Speak AO, Torres D, Fontaine J, Sheehan KCF, Capron M, Ryffel B, Faveeuw C, de Moraes ML, Platt F, Trottein F. Activation of Invariant NKT Cells by Toll-like Receptor 9-Stimulated Dendritic Cells Requires Type I Interferon and Charge Glycosphingolipids. Immunity, 27: 597-609 (2007).